Celluvance NAD Supplement Blend









Celluvance NAD Supplement Blend
★Recommended cadence, based on dosage & bottle size
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- Item Form
- Capsule
- Primary Supplement Type
- NAD+ Precursor + Longevity Blend
- Flavor
- Unflavored
- Product Benefits
- Cellular Energy, NAD+ Support, Longevity, Mitochondrial Health
- Diet Type
- Gluten Free, Non-GMO
- Supplement Formulation
- Combination Supplement (Blend)
- Best Taken
- With breakfast. Long-term daily use.
- Manufactured In
- USA, GMP-certified facility
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use, especially if you are pregnant, nursing, taking medications, or have a medical condition.
Celluvance -a comprehensive 10,573 mg NAD+ precursor and longevity blend combining NMN, NR, and supporting cofactors to raise intracellular NAD+ levels, support mitochondrial health, and promote cellular resilience.
Why It Works
Why NAD+ Is the Longevity Molecule Your Cells Need
NAD+ Declines With Age
NAD+ (nicotinamide adenine dinucleotide) falls by roughly 50% between ages 40 and 60 in most tissues. This decline is directly tied to reduced mitochondrial function, slower DNA repair, impaired sirtuin activity, and the general decrease in cellular resilience that characterizes aging.
NMN and NR Raise Intracellular NAD+
NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are the two most studied oral NAD+ precursors. Human trials show that both significantly raise blood and tissue NAD+ levels within days of supplementation -NMN at 250–1,000 mg doses and NR at 250–500 mg doses.
Supports Sirtuin Activity
Sirtuins are NAD+-dependent enzymes that regulate gene expression, DNA repair, and mitochondrial biogenesis. Raising NAD+ supports the sirtuin system -a pathway closely associated with the beneficial effects of caloric restriction and longevity research.
Mitochondrial Function and Endurance
NAD+ is essential for the electron transport chain that generates ATP in mitochondria. Restoring NAD+ levels in aged muscle supports mitochondrial efficiency, contributing to improved endurance capacity -a benefit observed in human trials measuring VO2 parameters.
DNA Repair Support
PARP enzymes -which detect and repair damaged DNA -are major consumers of NAD+. When NAD+ is depleted, DNA damage accumulates faster. Supplementing NAD+ precursors helps support the repair capacity that keeps cellular integrity intact over time.
Supporting Cofactors in the Blend
Beyond NMN and NR, the Celluvance blend includes resveratrol (sirtuin activator), TMG (methylation support to offset SAM depletion from NMN), and other longevity-oriented cofactors. These are commonly stacked with NAD+ precursors in longevity protocols.
NAD+ Elevation
Human Trials Show Meaningful NAD+ Elevation From Oral Precursors
Two key human RCTs show that oral NMN at 250–500 mg/day increases blood NAD+ by 40–60% within 4 weeks; oral NR at 1,000 mg/day raised whole-blood NAD+ by approximately 40–90% in multiple trials. The Celluvance blend combines both precursors at meaningful doses within its comprehensive formulation.
0%
55%
40%
60%
Approximate % increase in blood NAD+ vs baseline
*Trammell et al. (2016), Irie et al. (2020), Yi et al. (2023). Individual variation is significant.
Your Journey
What to Expect Over 3 Months

Foundation
Month 1
In the first 2–4 weeks, most users notice improved mental clarity, more consistent energy throughout the day, and less of the mid-afternoon fatigue that is characteristic of declining NAD+ in metabolically active tissues.
These early effects reflect cellular energy production improving at the mitochondrial level -changes that can occur relatively quickly once NAD+ levels begin to rise in blood and tissues.
Better Together
Combines Well With
Stack with these for a complete protocol, formulated to work synergistically.
Got Questions?
Frequently Asked Questions
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