L-Glutamine
L-Glutamine
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- Item Form
- Capsule
- Primary Supplement Type
- L-Glutamine (Free-Form Amino Acid)
- Flavor
- Unflavored
- Product Benefits
- Gut Lining Support, Leaky Gut, Muscle Recovery, Immune Health
- Diet Type
- Gluten Free, Vegan, Non-GMO
- Supplement Formulation
- Individual Supplement
- Best Taken
- On an empty stomach or post-workout
- Manufactured In
- USA, GMP-certified facility
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use, especially if you are pregnant, nursing, taking medications, or have a medical condition.
L-Glutamine 1,000 mg per capsule -the conditionally essential amino acid that fuels intestinal cells, supports tight-junction repair in a leaky gut, and accelerates post-workout muscle recovery.
Why It Works
Why L-Glutamine Is the First Amino Acid Your Gut Needs
Primary Fuel for Intestinal Cells
Enterocytes -the cells lining your small intestine -rely on glutamine as their principal energy source, consuming it faster than glucose. Adequate glutamine supply helps these cells maintain the structural integrity of the intestinal wall.
Supports Tight Junction Repair
Research shows glutamine supplementation supports the upregulation of tight-junction proteins including claudin-1, occludin, and ZO-1 -the molecular "seals" between intestinal cells that prevent unwanted substances from crossing into circulation.
Reduces Post-Exercise Muscle Breakdown
During intense exercise, muscle glutamine stores are depleted rapidly. Supplementing L-Glutamine supports a positive nitrogen balance, reducing muscle catabolism and helping your body shift into recovery mode sooner after training.
Immune System Fuel
Rapidly dividing immune cells -including lymphocytes and macrophages -use glutamine as a preferred fuel source. Maintaining adequate levels is especially important during periods of high physical or metabolic stress when the immune system's demand rises sharply.
Reduces Gut Permeability Under Stress
Clinical research demonstrates that glutamine supplementation significantly reduces intestinal permeability in patients under metabolic or physical stress -supporting the barrier that separates the gut microbiome from the bloodstream.
Supports Healthy Mucus Layer
Glutamine supports goblet cell function in the intestinal lining -the cells responsible for producing the mucus layer that lubricates and protects the gut wall from irritation and microbial imbalance.
Intestinal Permeability Reduction
The Evidence for Glutamine and the Gut Barrier
Clinical studies measuring lactulose/mannitol ratios -the gold standard for intestinal permeability -consistently show that L-Glutamine supplementation meaningfully reduces gut leakiness, particularly in stressed or depleted states. The effect is dose-dependent and cumulative with consistent daily use.
100%
78%
60%
Intestinal permeability (% of baseline, lower = better)
*Based on lactulose/mannitol ratio outcomes in controlled human supplementation trials.
Your Journey
What to Expect Over 3 Months
Foundation
Month 1
In the first few weeks, people with digestive sensitivity often notice a calmer gut -less bloating after meals, fewer episodes of cramping, and more consistent bowel function. Those using it for fitness recovery typically feel less muscle soreness within 72 hours post-workout.
These early effects reflect glutamine replenishing the rapidly cycling enterocyte and immune cell pools.
Better Together
Combines Well With
Stack with these for a complete protocol, formulated to work synergistically.
Got Questions?
Frequently Asked Questions
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